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《Nature Reviews MCB》-Telomeres in cancer

4

Telomeres in cancer: tumour suppression and genome instability Abstract The shortening of human telomeres has two opposing effects during cancer development. On the one hand, telo ...

  • 发表于:昨天 15:16
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  • 《Nature Reviews Cancer》-cancer precision medicine with PDXs

    6

    Interrogating open issues in cancer precision medicine with patient-derived xenografts Abstract Patient-derived xenografts (PDXs) have emerged as an important platform to elucidat ...

  • 发表于:昨天 15:14
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  • 《Circ Res》-lncRNA与心肌重塑

    3

    Long Noncoding RNAs in Pathological Cardiac Remodeling. AbstractA novel long noncoding RNA Chaer acts as noncoding epigenetic regulator at the onset of cardiac hypertrophy and enab ...

  • 发表于:昨天 14:00
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  • 《Circ Res》-循环ncRNA与心血管疾病

    4

    Circulating Noncoding RNAs as Biomarkers of Cardiovascular Disease and Injury. AbstractThe discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on mammalian geno ...

  • 发表于:昨天 13:59
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  • 《Brief Bioinform》-RNA-seq研究的样品大小估算

    29

    Feasibility of sample size calculation for RNA-seq studies. AbstractSample size calculation is a crucial step in study design but is not yet fully established for RNA sequencing (R ...

  • 发表于:前天 13:50
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  • 《Genet Med》-A taxonomy of medical uncertainties in clinical NGS

    9

    A taxonomy of medical uncertainties in clinical genome sequencing. AbstractPURPOSE:Clinical next-generation sequencing (CNGS) is introducing new opportunities and challenges into t ...

  • 发表于:前天 13:47
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  • 《PLoS Comput Biol》-Identifying TCR from NGS

    9

    Identifying T Cell Receptors from High-Throughput Sequencing: Dealing with Promiscuity in TCRα and TCRβ Pairing. AbstractCharacterisation of the T cell receptors (TCR) involved i ...

  • 发表于:前天 13:46
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  • 《Br J Cancer》-Tissue-based NGS:application in healthcare system

    9

    Tissue-based next generation sequencing: application in a universal healthcare system. AbstractIn the context of solid tumours, the evolution of cancer therapies to more targeted a ...

  • 发表于:前天 13:44
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  • 《Genome Res》-无参考压缩数据与人基因组测序数据分析

    5

    Using reference-free compressed data structures to analyze sequencing reads from thousands of human genomes AbstractWe are rapidly approaching the point where we have sequenced mil ...

  • 发表于:前天 13:41
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  • 《Pediatrics》-基因组医学与新生儿测序

    6

    Newborn Sequencing in Genomic Medicine and Public Health. AbstractThe rapid development of genomic sequencing technologies has decreased the cost of genetic analysis to the extent ...

  • 发表于:3 天前
  • 0条评论
  • 【代码分享】用Python绘制小提琴图

    20

    【代码分享】用Python绘制小提琴图预备知识:小提琴图哪里好? 首先我们来看一个示例,下图通过小提琴图展示了疾病组和健康组的不同物种分类对应的相对丰度分布。 是不是感觉图形优美、信息量 ...

  • 发表于:3 天前
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  • 《Cell Rep》-成人神经干细胞的单细胞转录组分析

    6

    Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage. AbstractNeural stem cells (NSCs) in the adult mammalia ...

  • 发表于:3 天前
  • 0条评论
  • 《Stem Cells》-iPSC in the Era of Precision Medicine

    2

    Induced Pluripotent Stem Cell Research in the Era of Precision Medicine. AbstractRecent advances in DNA sequencing technologies are revealing how human genetic variations associate ...

  • 发表于:3 天前
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  • 《Genome Res》-HySA:单分子NGS与杂合结构性变异组装

    2

    HySA: A Hybrid Structural variant Assembly approach using next generation and single-molecule sequencing technologies AbstractAchieving complete, accurate and cost-effective assemb ...

  • 发表于:3 天前
  • 0条评论
  • 『锐帮读』产碳青霉烯酶肠杆菌属的全基因组分析

    6

    『锐帮读』产碳青霉烯酶肠杆菌属的全基因组分析导读:肠杆菌属(Enterobacter spp.)是造成医院内感染的主要病原菌,而碳青霉烯类抗生素被认为是为数不多的可以治疗此类病原菌感染的抗生素之一 ...

  • 发表于:3 天前
  • 0条评论
  • 《Epigenomics》-急淋白血病AS-lncRNA与DNA甲基化

    6

    Hypermethylation of antisense long noncoding RNAs in acute lymphoblastic leukemia. AbstractAIM:Long noncoding RNAs serve critical regulatory functions highly specific for a tissue ...

  • 发表于:4 天前
  • 0条评论
  • 《Genome Biology》-转录组测序与胎儿埃博拉病毒感染预后

    4

    Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus AbstractBackgroundIn 2014, Western Africa experienced an unanticipated expl ...

  • 发表于:4 天前
  • 0条评论
  • 《Genome Biology》-genomic analysis of coding and non-coding disease mutations

    12

    iRegNet3D: three-dimensional integrated regulatory network for the genomic analysis of coding and non-coding disease mutations AbstractThe mechanistic details of most disease-causi ...

  • 发表于:4 天前
  • 0条评论
  • 《Genome Res》-genome assembly from long uncorrected reads

    11

    Fast and accurate de novo genome assembly from long uncorrected reads AbstractThe assembly of long reads from Pacific Biosciences and Oxford Nanopore Technologies typically require ...

  • 发表于:4 天前
  • 0条评论
  • 『锐帮读』最全的猪肠道菌群参考基因集

    6

    『锐帮读』最全的猪肠道菌群参考基因集导读:猪是畜产品的主要来源,通常作为首选模式物种应用于人体多种生理功能和疾病分析。人体肠道基因集对揭示肠道微生物和宿主生理功能间的相互关系起到巨 ...

  • 发表于:4 天前
  • 0条评论
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