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《Sci China Life Sci》-循环cfDNA甲基化标签与肿瘤早期检测

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DNA methylation signatures in circulating cell-free DNA as biomarkers for the early detection of cancer. AbstractDetecting cell-free DNA (cfDNA) or circulating tumor DNA (ctDNA) in ...

  • 发表于:昨天 13:49
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  • 《Oncogene》-Analysis of DNA methylation in single CTCs

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    Analysis of DNA methylation in single circulating tumor cells. AbstractDirect analysis of circulating tumor cells (CTCs) can inform on molecular mechanisms underlying systemic spre ...

  • 发表于:昨天 13:45
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  • 《Curr Opin Genet Dev》-The timing of zygotic genome activation

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    The timing of zygotic genome activation. AbstractAfter fertilization, the embryonic genome is inactive until transcription is initiated during the maternal-to-zygotic transition. H ...

  • 发表于:昨天 10:11
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  • 《Circ Cardiovasc Genet》-外显子组测序与先天性心脏病诊治

    4

    Application of Whole Exome Sequencing in the Clinical Diagnosis and Management of Inherited Cardiovascular Diseases in Adults. AbstractBACKGROUND:With the advent of high throughput ...

  • 发表于:昨天 10:08
  • 0条评论
  • 《Cancer》-NSCLC针吸样本的NGS

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    Next-generation sequencing of liquid-based cytology non-small cell lung cancer samples. AbstractBACKGROUND:The detection of mutated epidermal growth factor receptor (EGFR) in non-s ...

  • 发表于:前天 10:52
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  • 《Genet Med》-newborn genomic sequencing

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    A curated gene list for reporting results of newborn genomic sequencing. AbstractPURPOSE:Genomic sequencing (GS) for newborns may enable detection of conditions for which early kno ...

  • 发表于:3 天前
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  • 《Genome Res》-哺乳动物原始microRNA的加工

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    Novel determinants of mammalian primary microRNA processing revealed by systematic evaluation of hairpin-containing transcripts and human genetic variation AbstractMature microRNAs ...

  • 发表于:3 天前
  • 0条评论
  • 《Genome Res》-哺乳动物原始microRNA的加工

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    Novel determinants of mammalian primary microRNA processing revealed by systematic evaluation of hairpin-containing transcripts and human genetic variation AbstractMature microRNAs ...

  • 发表于:3 天前
  • 0条评论
  • 《Genome Res》-急淋白血病的全转录组测序

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    Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP AbstractChromosomal transloc ...

  • 发表于:3 天前
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  • 《Genome Res》-鱼类免疫细胞的单细胞转录组分析

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    Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types AbstractThe immune system of vertebrate species consists ...

  • 发表于:3 天前
  • 0条评论
  • 《BBA》-Making sense of genomic intra-tumour heterogeneity

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    Catch my drift? Making sense of genomic intra-tumour heterogeneity. AbstractThe cancer genome is shaped by three components of the evolutionary process: mutation, selection and dri ...

  • 发表于:4 天前
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  • 《Bioinformatics》-KNIME4NGS: a comprehensive toolbox for Next

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    KNIME4NGS: a comprehensive toolbox for Next. AbstractAnalysis of Next Generation Sequencing (NGS) data requires the processing of large datasets by chaining various tools with comp ...

  • 发表于:4 天前
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  • 《Cell Metab》-Enriching the Circadian Proteome

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    Enriching the Circadian Proteome. AbstractCircadian clocks regulate most aspects of physiology and metabolism. Genome-wide approaches have uncovered widespread circadian rhythms in ...

  • 发表于:4 天前
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  • 《Brief Bioinform》-miRDis:microRNA discovery based on NGS

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    miRDis: a Web tool for endogenous and exogenous microRNA discovery based on deep-sequencing data analysis. AbstractSmall RNA sequencing is the most widely used tool for microRNA (m ...

  • 发表于:4 天前
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  • 《Brief Bioinform》-find exon chains based on long reads

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    Evaluating approaches to find exon chains based on long reads. AbstractTranscript prediction can be modeled as a graph problem where exons are modeled as nodes and reads spanning t ...

  • 发表于:5 天前
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  • 《Cancer Med》-靶向NGS与急粒白血病风险分层

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    A targeted next-generation sequencing in the molecular risk stratification of adult acute myeloid leukemia: implications for clinical practice. AbstractConventional cytogenetics ca ...

  • 发表于:5 天前
  • 0条评论
  • 《Hepatology》-肝脏特异性lncRNA与非酒精性脂肪性肝炎

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    A liver-specific long non-coding RNA with a role in cell viability is elevated in human non-alcoholic steatohepatitis. AbstractHepatocyte apoptosis in non-alcoholic steatohepatitis ...

  • 发表于:5 天前
  • 0条评论
  • 《Genome Biology》-ES中poly(A) RNA的不同5-甲基胞嘧啶变化

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    Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain AbstractBackgroundRecent work has identified and mapped a range of posttranscriptional m ...

  • 发表于:5 天前
  • 0条评论
  • 《Nature》-Genomic hallmarks of non-indolent prostate cancer

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    Genomic hallmarks of localized, non-indolent prostate cancer. AbstractProstate tumours are highly variable in their response to therapies, but clinically available prognostic facto ...

  • 发表于:6 天前
  • 0条评论
  • 《Brief Bioinform》-Exploiting NGS to solve polyploids

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    Exploiting next-generation sequencing to solve the haplotyping puzzle in polyploids: a simulation study. AbstractHaplotypes are the units of inheritance in an organism, and many ge ...

  • 发表于:6 天前
  • 0条评论
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